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Page 1
Activin signal transduction in the fetal rat adrenal gland and in human H295R cells.
Wang EY, Ma EY, Woodruff TK. Wang EY, et al. J Endocrinol. 2003 Jul;178(1):137-48. doi: 10.1677/joe.0.1780137. J Endocrinol. 2003. PMID: 12844345
The presence of activin A and its effects have previously been documented in the adrenal gland, particularly in the human fetal adrenal gland and the rat adrenal gland. ...In determining activin's effects on adrenal function, adrenal steroid production …
The presence of activin A and its effects have previously been documented in the adrenal gland, particularly in the human feta …
The EGF-CFC family: novel epidermal growth factor-related proteins in development and cancer.
Saloman DS, Bianco C, Ebert AD, Khan NI, De Santis M, Normanno N, Wechselberger C, Seno M, Williams K, Sanicola M, Foley S, Gullick WJ, Persico G. Saloman DS, et al. Endocr Relat Cancer. 2000 Dec;7(4):199-226. doi: 10.1677/erc.0.0070199. Endocr Relat Cancer. 2000. PMID: 11174844 Review.
Recombinant mouse or human cripto can enhance cell motility and branching morphogenesis in mammary epithelial cells and in some human tumor cells. ...Although a specific receptor for the EGF-CFC proteins has not yet been identified, oep depends upon an activin …
Recombinant mouse or human cripto can enhance cell motility and branching morphogenesis in mammary epithelial cells and in some hu …
Regulation of myostatin activity and muscle growth.
Lee SJ, McPherron AC. Lee SJ, et al. Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9306-11. doi: 10.1073/pnas.151270098. Epub 2001 Jul 17. Proc Natl Acad Sci U S A. 2001. PMID: 11459935 Free PMC article.
The purified C-terminal myostatin dimer was capable of binding the activin type II receptors, Act RIIB and, to a lesser extent, Act RIIA. Binding of myostatin to Act RIIB could be inhibited by the activin-binding protein follistatin and, at higher conc …
The purified C-terminal myostatin dimer was capable of binding the activin type II receptors, Act RIIB and, to a lesser extent …
A Pdx-1-Regulated Soluble Factor Activates Rat and Human Islet Cell Proliferation.
Hayes HL, Zhang L, Becker TC, Haldeman JM, Stephens SB, Arlotto M, Moss LG, Newgard CB, Hohmeier HE. Hayes HL, et al. Mol Cell Biol. 2016 Nov 14;36(23):2918-2930. doi: 10.1128/MCB.00103-16. Print 2016 Dec 1. Mol Cell Biol. 2016. PMID: 27620967 Free PMC article.
Overexpression of Inhbb or addition of activin B stimulates rat islet cell and beta-cell proliferation, and the activin receptors RIIA and RIIB are required for the full proliferative effects of Pdx-1 in rat islets. ...In sum, this study identifies a mechanis …
Overexpression of Inhbb or addition of activin B stimulates rat islet cell and beta-cell proliferation, and the activin recept …
Activin and transforming growth factor-beta signaling pathways are activated after allergen challenge in mild asthma.
Kariyawasam HH, Pegorier S, Barkans J, Xanthou G, Aizen M, Ying S, Kay AB, Lloyd CM, Robinson DS. Kariyawasam HH, et al. J Allergy Clin Immunol. 2009 Sep;124(3):454-62. doi: 10.1016/j.jaci.2009.06.022. J Allergy Clin Immunol. 2009. PMID: 19733294 Free PMC article.
OBJECTIVE: To define the expression kinetics of TGF-beta(1), activin-A ligands, and follistatin (a natural activin inhibitor), their type I and type II receptors (activin-like kinase[ALK]-1, ALK-5, ALK-4, TbetaRII, and ActRIIA/RIIB) and activation of s …
OBJECTIVE: To define the expression kinetics of TGF-beta(1), activin-A ligands, and follistatin (a natural activin inhibitor), …
Down-regulation of activin, activin receptors, and Smads in high-grade breast cancer.
Jeruss JS, Sturgis CD, Rademaker AW, Woodruff TK. Jeruss JS, et al. Cancer Res. 2003 Jul 1;63(13):3783-90. Cancer Res. 2003. PMID: 12839974
The presence of the major components of the activin signal transduction pathway in different pathologic grades of breast cancer tissue has not been described thoroughly, despite evidence from in vitro studies suggesting that activin can inhibit proliferation in brea …
The presence of the major components of the activin signal transduction pathway in different pathologic grades of breast cancer tissu …
Effect of bone morphogenetic protein-6 on macrophages.
Hong JH, Lee GT, Lee JH, Kwon SJ, Park SH, Kim SJ, Kim IY. Hong JH, et al. Immunology. 2009 Sep;128(1 Suppl):e442-50. doi: 10.1111/j.1365-2567.2008.02998.x. Epub 2008 Dec 23. Immunology. 2009. PMID: 19191909 Free PMC article.
Reverse transcription-polymerase chain reaction (RT-PCR) analysis demonstrated the expression of all three known type II BMP receptors [BMP-RII, activin (Act)-RIIA and Act-RIIB] and two of the three known type I receptors [activin receptor-like kinase 2 (ALK2 …
Reverse transcription-polymerase chain reaction (RT-PCR) analysis demonstrated the expression of all three known type II BMP receptors [BMP- …